PCR Mutation Detection Protocols
Andrea M. Guilliatt (auth.), Bimal D. M. Theophilus, Ralph Rapley (eds.)
Bimal D. Theophilus and Ralph Rapley provide biological and clinical investigators with a comprehensive collection of new, recent, and updated PCR-based screening methods suitable for detecting the presence of both known and novel mutations. The methods cover point mutations (e.g., ASO-PCR, SSCP, DGGE, chemical cleavage), deletions (multiplex PCR, FISH, blotting), non-sense mutations (PTT), and more. The new and exciting techniques of DNA array analysis, along with such recently developed experimental methods as conformation-sensitive gel electrophoresis, are also included. Each chapter explains the basic theory behind the technique and provides valuable notes essential for its successful execution.
หมวดหมู่:
ปี:
2002
ฉบับพิมพ์ครั้งที่:
1
สำนักพิมพ์:
Humana Press
ภาษา:
english
จำนวนหน้า:
224
ISBN 10:
0896036170
ISBN 13:
9780896036178
ซีรีส์:
Methods in Molecular Biology 187
ไฟล์:
PDF, 1.01 MB
IPFS:
,
english, 2002
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